Crossover interference underlies sex differences in recombination rates.

نویسندگان

  • Petko M Petkov
  • Karl W Broman
  • Jin P Szatkiewicz
  • Kenneth Paigen
چکیده

In many organisms, recombination rates differ between the two sexes. Here we show that in mice, this is because of a shorter genomic interference distance in females than in males, measured in Mb. However, the interference distance is the same in terms of bivalent length. We propose a model in which the interference distance in the two sexes reflects the compaction of chromosomes at the pachytene stage of meiosis.

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Crossover interference underlies higher recombination rates in females

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عنوان ژورنال:
  • Trends in genetics : TIG

دوره 23 11  شماره 

صفحات  -

تاریخ انتشار 2007